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Considerations When Using Breast Cancer Risk Models for Women with Negative BRCA1/BRCA2 Mutation Results

The performance of breast cancer risk models for women with a family history but negative BRCA1 and/or BRCA2 mutation test results is uncertain. We calculated the cumulative 10-year invasive breast cancer risk at cohort entry for 14 657 unaffected women (96.1% had an affected relative) not known to...

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Veröffentlicht in:J Natl Cancer Inst
Hauptverfasser: MacInnis, Robert J, Liao, Yuyan, Knight, Julia A, Milne, Roger L, Whittemore, Alice S, Chung, Wendy K, Leoce, Nicole, Buchsbaum, Richard, Zeinomar, Nur, Dite, Gillian S, Southey, Melissa C, Goldgar, David, Giles, Graham G, McLachlan, Sue-Anne, Weideman, Prue C, Nesci, Stephanie, Friedlander, Michael L, Glendon, Gord, Andrulis, Irene L, John, Esther M, Daly, Mary B, Buys, Saundra S, Phillips, Kelly Anne, Hopper, John L, Terry, Mary Beth
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2019
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7156937/
https://ncbi.nlm.nih.gov/pubmed/31584660
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jnci/djz194
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