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CdbA is a DNA-binding protein and c-di-GMP receptor important for nucleoid organization and segregation in Myxococcus xanthus

Cyclic di-GMP (c-di-GMP) is a second messenger that modulates multiple responses to environmental and cellular signals in bacteria. Here we identify CdbA, a DNA-binding protein of the ribbon-helix-helix family that binds c-di-GMP in Myxococcus xanthus. CdbA is essential for viability, and its deplet...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Skotnicka, Dorota, Steinchen, Wieland, Szadkowski, Dobromir, Cadby, Ian T., Lovering, Andrew L., Bange, Gert, Søgaard-Andersen, Lotte
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7156744/
https://ncbi.nlm.nih.gov/pubmed/32286293
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-15628-8
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