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Minimum epistasis interpolation for sequence-function relationships

Massively parallel phenotyping assays have provided unprecedented insight into how multiple mutations combine to determine biological function. While such assays can measure phenotypes for thousands to millions of genotypes in a single experiment, in practice these measurements are not exhaustive, s...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Zhou, Juannan, McCandlish, David M.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7156698/
https://ncbi.nlm.nih.gov/pubmed/32286265
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-15512-5
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