A common polymorphism in the retinoic acid pathway modifies adrenocortical carcinoma age-dependent incidence

BACKGROUND: Genome-wide association studies (GWASs) have enriched the fields of genomics and drug development. Adrenocortical carcinoma (ACC) is a rare cancer with a bimodal age distribution and inadequate treatment options. Paediatric ACC is frequently associated with TP53 mutations, with particula...

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Pubblicato in:Br J Cancer
Autori principali: Surakhy, Mirvat, Wallace, Marsha, Bond, Elisabeth, Grochola, Lukasz Filip, Perez, Husein, Di Giovannantonio, Matteo, Zhang, Ping, Malkin, David, Carter, Hannah, Parise, Ivy Zortea S., Zambetti, Gerard, Komechen, Heloisa, Paraizo, Mariana M., Pagadala, Meghana S., Pinto, Emilia M., Lalli, Enzo, Figueiredo, Bonald C., Bond, Gareth L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2020
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7156685/
https://ncbi.nlm.nih.gov/pubmed/32147670
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41416-020-0764-3
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