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Reducing endogenous insulin is linked with protection against hepatic steatosis in mice

BACKGROUND: Obesity and type 2 diabetes (T2D) are closely associated with hepatic steatosis (HS), which if untreated can advance to serious liver conditions. Since insulin promotes hepatic lipogenesis, reducing hyperinsulinemia may help in treating HS. E4orf1 is an adenovirus-derived protein that im...

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Опубликовано в: :Nutr Diabetes
Главные авторы: Akheruzzaman, Md, Hegde, Vijay, Shin, Andrew C., Dhurandhar, Nikhil V.
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Publishing Group UK 2020
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7156670/
https://ncbi.nlm.nih.gov/pubmed/32286259
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41387-020-0114-9
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