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Reducing endogenous insulin is linked with protection against hepatic steatosis in mice

BACKGROUND: Obesity and type 2 diabetes (T2D) are closely associated with hepatic steatosis (HS), which if untreated can advance to serious liver conditions. Since insulin promotes hepatic lipogenesis, reducing hyperinsulinemia may help in treating HS. E4orf1 is an adenovirus-derived protein that im...

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Detalhes bibliográficos
Publicado no:Nutr Diabetes
Main Authors: Akheruzzaman, Md, Hegde, Vijay, Shin, Andrew C., Dhurandhar, Nikhil V.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7156670/
https://ncbi.nlm.nih.gov/pubmed/32286259
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41387-020-0114-9
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