Functionalized Enzyme-Responsive Biomaterials to Model Tissue Stiffening in vitro

The mechanical properties of the cellular microenvironment play a crucial role in modulating cell function, and many pathophysiological processes are accompanied by variations in extracellular matrix (ECM) stiffness. Lysyl oxidase (LOx) is one of the enzymes involved in several ECM-stiffening proces...

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Dades bibliogràfiques
Publicat a:Front Bioeng Biotechnol
Autors principals: Tirella, Annalisa, Mattei, Giorgio, La Marca, Margherita, Ahluwalia, Arti, Tirelli, Nicola
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2020
Matèries:
Bioengineering and Biotechnology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7156543/
https://ncbi.nlm.nih.gov/pubmed/32322576
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fbioe.2020.00208
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