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Crosstalk between hydroxytyrosol, a major olive oil phenol, and HIF-1 in MCF-7 breast cancer cells

Olive oil intake has been linked with a lower incidence of breast cancer. Hypoxic microenvironment in solid tumors, such as breast cancer, is known to play a crucial role in cancer progression and in the failure of anticancer treatments. HIF-1 is the foremost effector in hypoxic response, and given...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Calahorra, Jesús, Martínez-Lara, Esther, Granadino-Roldán, José M., Martí, Juan M., Cañuelo, Ana, Blanco, Santos, Oliver, F. Javier, Siles, Eva
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7156391/
https://ncbi.nlm.nih.gov/pubmed/32286485
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-63417-6
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