Alarmin-painted exosomes elicit persistent antitumor immunity in large established tumors in mice

Treating large established tumors is challenging for dendritic cell (DC)-based immunotherapy. DC activation with tumor cell-derived exosomes (TEXs) carrying multiple tumor-associated antigen can enhance tumor recognition. Adding a potent adjuvant, high mobility group nucleosome-binding protein 1 (HM...

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Veröffentlicht in:Nat Commun
Hauptverfasser: Zuo, Bingfeng, Qi, Han, Lu, Zhen, Chen, Lu, Sun, Bo, Yang, Rong, Zhang, Yang, Liu, Zhili, Gao, Xianjun, You, Abin, Wu, Li, Jing, Renwei, Zhou, Qibing, Yin, HaiFang
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2020
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7156382/
https://ncbi.nlm.nih.gov/pubmed/32286296
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-15569-2
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