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Polygenic disruption of retinoid signalling in schizophrenia and a severe cognitive deficit subtype

Retinoid metabolites of vitamin A are intrinsically linked to neural development, connectivity and plasticity, and have been implicated in the pathophysiology of schizophrenia. We hypothesised that a greater burden of common and rare genomic variation in genes involved with retinoid biogenesis and s...

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Vydáno v:Mol Psychiatry
Hlavní autoři: Reay, William R., Atkins, Joshua R., Quidé, Yann, Carr, Vaughan J., Green, Melissa J., Cairns, Murray J.
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7156344/
https://ncbi.nlm.nih.gov/pubmed/30532020
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41380-018-0305-0
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