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High circulating elafin levels are associated with Crohn’s disease-associated intestinal strictures

BACKGROUND: Antimicrobial peptide expression is associated with disease activity in inflammatory bowel disease (IBD) patients. IBD patients have abnormal expression of elafin, a human elastase-specific protease inhibitor and antimicrobial peptide. We determined elafin expression in blood, intestine,...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Wang, Jiani, Ortiz, Christina, Fontenot, Lindsey, Xie, Ying, Ho, Wendy, Mattai, S. Anjani, Shih, David Q., Koon, Hon Wai
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7156098/
https://ncbi.nlm.nih.gov/pubmed/32287314
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0231796
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