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Establishing a nonlethal and efficient mouse model of male gonadotoxicity by intraperitoneal busulfan injection
An ideal animal model of azoospermia would be a powerful tool for the evaluation of spermatogonial stem cell (SSC) transplantation. Busulfan has been commonly used to develop such a model, but 30%–87% of mice die when administered an intraperitoneal injection of 40 mg kg(−1). In the present study, h...
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| Опубликовано в: : | Asian J Androl |
|---|---|
| Главные авторы: | , , , , , , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Wolters Kluwer - Medknow
2019
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7155790/ https://ncbi.nlm.nih.gov/pubmed/31187778 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4103/aja.aja_41_19 |
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