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Orotic acid-treated hepatocellular carcinoma cells resist steatosis by modification of fatty acid metabolism

BACKGROUND: Orotic acid (OA) has been intensively utilized to induce fatty liver in rats. Although the capacity of OA to cause steatosis is species-specific, previous in vitro studies indicate that humans could also be susceptible to OA-induced fatty liver. The aim of the present study was to re-elu...

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Detalhes bibliográficos
Publicado no:Lipids Health Dis
Main Authors: Matilainen, Johanna, Mustonen, Anne-Mari, Rilla, Kirsi, Käkelä, Reijo, Sihvo, Sanna P., Nieminen, Petteri
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7155272/
https://ncbi.nlm.nih.gov/pubmed/32284043
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12944-020-01243-5
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