Probing the Open Global Health Chemical Diversity Library for Multistage-Active Starting Points for Next-Generation Antimalarials

[Image: see text] Most phenotypic screens aiming to discover new antimalarial chemotypes begin with low cost, high-throughput tests against the asexual blood stage (ABS) of the malaria parasite life cycle. Compounds active against the ABS are then sequentially tested in more difficult assays that pr...

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Foilsithe in:ACS Infect Dis
Main Authors: Abraham, Matthew, Gagaring, Kerstin, Martino, Marisa L., Vanaerschot, Manu, Plouffe, David M., Calla, Jaeson, Godinez-Macias, Karla P., Du, Alan Y., Wree, Melanie, Antonova-Koch, Yevgeniya, Eribez, Korina, Luth, Madeline R., Ottilie, Sabine, Fidock, David A., McNamara, Case W., Winzeler, Elizabeth A.
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Chemical Society 2020
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7155171/
https://ncbi.nlm.nih.gov/pubmed/32078764
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsinfecdis.9b00482
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