Cerebral oxygen metabolism in adults with sickle cell disease

In sickle cell disease (SCD), oxygen delivery is impaired due to anemia, especially during times of increased metabolic demand, and cerebral blood flow (CBF) must increase to meet changing physiologic needs. But hyperemia limits cerebrovascular reserve (CVR) and ischemic risk prevails despite elevat...

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Dades bibliogràfiques
Publicat a:Am J Hematol
Autors principals: Václavů, Lena, Petr, Jan, Petersen, Esben Thade, Mutsaerts, Henri J.M.M., Majoie, Charles B.L., Wood, John C., VanBavel, Ed, Nederveen, Aart J., Biemond, Bart J.
Format: Artigo
Idioma:Inglês
Publicat: John Wiley & Sons, Inc. 2020
Matèries:
Research Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7155077/
https://ncbi.nlm.nih.gov/pubmed/31919876
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ajh.25727
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