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Cerebral oxygen metabolism in adults with sickle cell disease

In sickle cell disease (SCD), oxygen delivery is impaired due to anemia, especially during times of increased metabolic demand, and cerebral blood flow (CBF) must increase to meet changing physiologic needs. But hyperemia limits cerebrovascular reserve (CVR) and ischemic risk prevails despite elevat...

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Bibliografiska uppgifter
I publikationen:Am J Hematol
Huvudupphovsmän: Václavů, Lena, Petr, Jan, Petersen, Esben Thade, Mutsaerts, Henri J.M.M., Majoie, Charles B.L., Wood, John C., VanBavel, Ed, Nederveen, Aart J., Biemond, Bart J.
Materialtyp: Artigo
Språk:Inglês
Publicerad: John Wiley & Sons, Inc. 2020
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC7155077/
https://ncbi.nlm.nih.gov/pubmed/31919876
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ajh.25727
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