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“In‐loop” carbonylation—A simplified method for carbon‐11 labelling of drugs and radioligands

Transition‐metal mediated carbonylation with (11)C‐labelled carbon monoxide ([(11)C]CO) is a versatile method for introducing (11)C (t (1/2) = 20.3 min) into drugs and radioligands for subsequent use in positron emission tomography (PET). The aim of the current study was to perform the (11)C‐carbony...

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Detalhes bibliográficos
Publicado no:J Labelled Comp Radiopharm
Main Authors: Ferrat, Mélodie, Dahl, Kenneth, Halldin, Christer, Schou, Magnus
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7155033/
https://ncbi.nlm.nih.gov/pubmed/31524295
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jlcr.3805
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