A Phase 1, Randomized, Open‐Label, Safety, Tolerability, and Comparative Bioavailability Study of Intranasal Dihydroergotamine Powder (STS101), Intramuscular Dihydroergotamine Mesylate, and Intranasal DHE Mesylate Spray in Healthy Adult Subjects

OBJECTIVE: To investigate and compare the safety and the pharmacokinetics of dihydroergotamine (DHE) after administration of intranasal DHE powder (STS101), intranasal DHE spray (Migranal(®)), and intramuscular (IM) DHE injection in healthy subjects. METHODS: This was a 2‐part, active‐controlled, 3‐...

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Bibliografische gegevens
Gepubliceerd in:Headache
Hoofdauteurs: Albrecht, Detlef, Iwashima, Mic, Dillon, Debbie, Harris, Stuart, Levy, Jeff
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: John Wiley and Sons Inc. 2020
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Research Submissions
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7154716/
https://ncbi.nlm.nih.gov/pubmed/31985049
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/head.13737
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