Cyclic helix B peptide ameliorates renal tubulointerstitial fibrosis induced by unilateral ureter obstruction via inhibiting NLRP3 pathway

BACKGROUND: Renal fibrosis is the inevitable outcome of all progressive chronic kidney diseases (CKD) and leads to a gradual loss of renal function. We previously reported cyclic helix B peptide (CHBP), a novel synthesized peptide derived from erythropoietin, had shown effective renoprotection. In t...

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Detalhes bibliográficos
Publicado no:Ann Transl Med
Main Authors: Qi, Ruochen, Zhang, Weitao, Zheng, Long, Xu, Ming, Rong, Ruiming, Zhu, Tongyu, Yang, Cheng
Formato: Artigo
Idioma:Inglês
Publicado em: AME Publishing Company 2020
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7154394/
https://ncbi.nlm.nih.gov/pubmed/32309314
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.21037/atm.2020.02.12
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