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miR-138 Increases Depressive-Like Behaviors by Targeting SIRT1 in Hippocampus

BACKGROUND: Major depressive disorder (MDD) is a serious and common mood disorder with unknown etiology. Emerging evidence has demonstrated the critical roles of SIRT1 and microRNAs (miRNAs) in the progression of MDD. However, the underlying molecular mechanisms remain to be fully understood. METHOD...

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Publicado en:Neuropsychiatr Dis Treat
Main Authors: Li, Cuixia, Wang, Feng, Miao, Pei, Yan, Libo, Liu, Silin, Wang, Xian, Jin, Zuolin, Gu, Zexu
Formato: Artigo
Idioma:Inglês
Publicado: Dove 2020
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7154038/
https://ncbi.nlm.nih.gov/pubmed/32308399
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/NDT.S237558
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