YAP in Kupffer cells enhances the production of pro-inflammatory cytokines and promotes the development of non-alcoholic steatohepatitis

Yes-associated protein (YAP) plays an important role in hepatocarcinogenesis, although the potential role of YAP in non-neoplastic liver diseases remains largely unknown. We report herein that YAP in Kupffer cells (KCs) enhances the production of pro-inflammatory cytokines and promotes the developme...

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Veröffentlicht in:Hepatology
Hauptverfasser: Song, Kyoungsub, Kwon, Hyunjoo, Han, Chang, Chen, Weina, Zhang, Janqiang, Ma, Wenbo, Dash, Srikanta, Gandhi, Chandrashekhar R., Wu, Tong
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2020
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7153981/
https://ncbi.nlm.nih.gov/pubmed/31610032
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.30990
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