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Aging: rewiring the circadian clock

The robustness of the circadian clock deteriorates with aging. Two new studies show that aging reprograms the circadian transcriptome in a cell-type-dependent manner and that such rewiring can be reversed by caloric restriction.

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Detalles Bibliográficos
Publicado en:Nat Struct Mol Biol
Main Authors: Ohkubo, Rika, Chen, Danica
Formato: Artigo
Idioma:Inglês
Publicado: 2017
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7153569/
https://ncbi.nlm.nih.gov/pubmed/28880862
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.3461
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