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Determining a Bayesian predictive power stopping rule for futility in a non-inferiority trial with binary outcomes

BACKGROUND/AIMS: Non-inferiority trials investigate whether a novel intervention, which typically has other benefits (i.e., cheaper or safer), has similar clinical effectiveness to currently available treatments. In situations where interim evidence in a non-inferiority trial suggests that the novel...

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Detalhes bibliográficos
Publicado no:Contemp Clin Trials Commun
Main Authors: Heath, Anna, Offringa, Martin, Pechlivanoglou, Petros, Rios, Juan David, Klassen, Terry P., Poonai, Naveen, Pullenayegum, Eleanor
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7153169/
https://ncbi.nlm.nih.gov/pubmed/32300671
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.conctc.2020.100561
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