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“Labile” heme critically regulates mitochondrial biogenesis through the transcriptional co-activator Hap4p in Saccharomyces cerevisiae

Heme (iron protoporphyrin IX) is a well-known prosthetic group for enzymes involved in metabolic pathways such as oxygen transport and electron transfer through the mitochondrial respiratory chain. However, heme has also been shown to be an important regulatory molecule (as “labile” heme) for divers...

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Bibliografske podrobnosti
izdano v:J Biol Chem
Main Authors: Bouchez, Cyrielle L., Yoboue, Edgar D., de la Rosa Vargas, Livier E., Salin, Bénédicte, Cuvellier, Sylvain, Rigoulet, Michel, Duvezin-Caubet, Stéphane, Devin, Anne
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2020
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7152774/
https://ncbi.nlm.nih.gov/pubmed/32075909
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA120.012739
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