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“Labile” heme critically regulates mitochondrial biogenesis through the transcriptional co-activator Hap4p in Saccharomyces cerevisiae

Heme (iron protoporphyrin IX) is a well-known prosthetic group for enzymes involved in metabolic pathways such as oxygen transport and electron transfer through the mitochondrial respiratory chain. However, heme has also been shown to be an important regulatory molecule (as “labile” heme) for divers...

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Veröffentlicht in:J Biol Chem
Hauptverfasser: Bouchez, Cyrielle L., Yoboue, Edgar D., de la Rosa Vargas, Livier E., Salin, Bénédicte, Cuvellier, Sylvain, Rigoulet, Michel, Duvezin-Caubet, Stéphane, Devin, Anne
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2020
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7152774/
https://ncbi.nlm.nih.gov/pubmed/32075909
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA120.012739
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