The dynein light chain 8 (LC8) binds predominantly “in-register” to a multivalent intrinsically disordered partner

Dynein light chain 8 (LC8) interacts with intrinsically disordered proteins (IDPs) and influences a wide range of biological processes. It is becoming apparent that among the numerous IDPs that interact with LC8, many contain multiple LC8-binding sites. Although it is established that LC8 forms para...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Principais autores: Reardon, Patrick N., Jara, Kayla A., Rolland, Amber D., Smith, Delaney A., Hoang, Hanh T. M., Prell, James S., Barbar, Elisar J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2020
Assuntos:
Protein Structure and Folding
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7152752/
https://ncbi.nlm.nih.gov/pubmed/32139510
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA119.011653
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