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Mechanochemical Formation of Racemic Praziquantel Hemihydrate with Improved Biopharmaceutical Properties

Praziquantel (PZQ) is the first-line drug used against schistosomiasis, one of the most common parasitic diseases in the world. A series of crystalline structures including two new polymorphs of the pure drug and a series of cocrystals of PZQ have been discovered and deposited in the Cambridge Struc...

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Vydáno v:Pharmaceutics
Hlavní autoři: Zanolla, Debora, Hasa, Dritan, Arhangelskis, Mihails, Schneider-Rauber, Gabriela, Chierotti, Michele R., Keiser, Jennifer, Voinovich, Dario, Jones, William, Perissutti, Beatrice
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7151222/
https://ncbi.nlm.nih.gov/pubmed/32210129
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/pharmaceutics12030289
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