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Topology, Antiviral Functional Residues and Mechanism of IFITM1

Interferon-inducible transmembrane proteins (IFITM1/2/3) have been reported to suppress the entry of a wide range of viruses. However, their antiviral functional residues and specific mechanisms are still unclear. Here, we firstly resolved the topology of IFITM1 on the plasma membrane where N-termin...

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Foilsithe in:Viruses
Main Authors: Sun, Fang, Xia, Zhiqiang, Han, Yuewen, Gao, Minjun, Wang, Luyao, Wu, Yingliang, Sabatier, Jean-Marc, Miao, Lixia, Cao, Zhijian
Formáid: Artigo
Teanga:Inglês
Foilsithe: MDPI 2020
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7150853/
https://ncbi.nlm.nih.gov/pubmed/32182730
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/v12030295
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