A Novel Bivalent Mannosylated Targeting Ligand Displayed on Nanoparticles Selectively Targets Anti-Inflammatory M2 Macrophages

Persistent activation of macrophages (MP)s into a proinflammatory M1 or anti-inflammatory M2 phenotype plays a role in several pathological conditions, including autoimmune diseases, fibrosis, infections, atherosclerosis and tumor development. The mannose receptor (MR, CD206), expressed at low level...

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Bibliographic Details
Published in:Pharmaceutics
Main Authors: Chen, Peiming, Zhang, Xiaoping, Venosa, Alessandro, Lee, In Heon, Myers, Daniel, Holloway, Jennifer A., Prud’homme, Robert K., Gao, Dayuan, Szekely, Zoltan, Laskin, Jeffery D., Laskin, Debra L., Sinko, Patrick J.
Format: Artigo
Language:Inglês
Published: MDPI 2020
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7150811/
https://ncbi.nlm.nih.gov/pubmed/32182675
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/pharmaceutics12030243
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