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Computational Study to Identify the Effects of the KCNJ2 E299V Mutation in Cardiac Pumping Capacity

The KCNJ2 gene mutations induce short QT syndrome (SQT3) by directly increasing the I(K1) current. There have been many studies on the electrophysiological effects of mutations such as the KCNJ2 D172N that cause the SQT3. However, the KCNJ2 E299V mutation is distinguished from other representative g...

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Bibliografski detalji
Izdano u:Comput Math Methods Med
Glavni autori: Jeong, Da Un, Lee, Jiyeong, Lim, Ki Moo
Format: Artigo
Jezik:Inglês
Izdano: Hindawi 2020
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7150720/
https://ncbi.nlm.nih.gov/pubmed/32328155
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2020/7194275
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