Oxidative stress-induced downregulation of glycogen synthase kinase 3 beta in fetal membranes promotes cellular senescence(†)

OBJECTIVE: Oxidative stress (OS)-induced stress signaler p38 mitogen-activated protein kinase (p38MAPK) activation and fetal membrane senescence are associated with parturition. This study determined changes in glycogen synthase kinase 3 beta (GSK3β) and its regulation by p38MAPK in effecting senesc...

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Udgivet i:Biol Reprod
Main Authors: Lavu, Narmada, Richardson, Lauren, Radnaa, Enkhtuya, Kechichian, Talar, Urrabaz-Garza, Rheanna, Sheller-Miller, Samantha, Bonney, Elizabeth, Menon, Ramkumar
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2019
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Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7150613/
https://ncbi.nlm.nih.gov/pubmed/31292604
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/biolre/ioz119
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