Aristolochic acid mutational signature defines the low-risk subtype in upper tract urothelial carcinoma

Rationale: Dietary exposure to aristolochic acids and similar compounds (collectively, AA) is a significant risk factor for nephropathy and subsequent upper tract urothelial carcinoma (UTUC). East Asian populations, who have a high prevalence of UTUC, have an unusual genome-wide AA-induced mutationa...

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Detalhes bibliográficos
Publicado no:Theranostics
Main Authors: Lu, Huan, Liang, Yuan, Guan, Bao, Shi, Yue, Gong, Yanqing, Li, Juan, Kong, Wenwen, Liu, Jin, Fang, Dong, Liu, Libo, He, Qun, Shakeel, Muhammad, Li, Xuesong, Zhou, Liqun, Ci, Weimin
Formato: Artigo
Idioma:Inglês
Publicado em: Ivyspring International Publisher 2020
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7150494/
https://ncbi.nlm.nih.gov/pubmed/32292497
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/thno.43251
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