Human CD8 T cells are susceptible to TNF-mediated activation-induced cell death

Activation-induced cell death (AICD) is a complex immunoregulatory mechanism that causes the demise of a fraction of T-lymphocytes upon antigen-driven activation. In the present study we investigated the direct role of TNF in AICD of CD8 T lymphocytes. Methods: Human peripheral mononuclear cells wer...

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Veröffentlicht in:Theranostics
Hauptverfasser: Otano, Itziar, Alvarez, Maite, Minute, Luna, Ochoa, María Carmen, Migueliz, Itziar, Molina, Carmen, Azpilikueta, Arantza, de Andrea, Carlos E., Etxeberria, Iñaki, Sanmamed, Miguel F., Teijeira, Álvaro, Berraondo, Pedro, Melero, Ignacio
Format: Artigo
Sprache:Inglês
Veröffentlicht: Ivyspring International Publisher 2020
Schlagworte:
Research Paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7150490/
https://ncbi.nlm.nih.gov/pubmed/32292509
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/thno.41646
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