SR9009 induces a REV-ERB dependent anti-small-cell lung cancer effect through inhibition of autophagy

Rationale: The circadian clock coordinates cell proliferation and metabolism and impacts the progression of some diseases, particularly cancer. Pharmacological modulation of the circadian machinery may be an effective therapeutic approach for treating cancer. SR9009 is a specific synthetic agonist o...

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Detalhes bibliográficos
Publicado no:Theranostics
Main Authors: Shen, Weitao, Zhang, Wei, Ye, Weilin, Wang, Haihong, Zhang, Qingxi, Shen, Jie, Hong, Qingsha, Li, Xiang, Wen, Ge, Wei, Ting, Zhang, Jian
Formato: Artigo
Idioma:Inglês
Publicado em: Ivyspring International Publisher 2020
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7150483/
https://ncbi.nlm.nih.gov/pubmed/32292508
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/thno.42478
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