PRMT5-dependent transcriptional repression of c-Myc target genes promotes gastric cancer progression

The proto-oncogene c-Myc regulates multiple biological processes mainly through selectively activating gene expression. However, the mechanisms underlying c-Myc-mediated gene repression in the context of cancer remain less clear. This study aimed to clarify the role of PRMT5 in the transcriptional r...

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Publicat a:Theranostics
Autors principals: Liu, Ming, Yao, Bing, Gui, Tao, Guo, Chan, Wu, Xiaobin, Li, Jiahuang, Ma, Lingling, Deng, Yexuan, Xu, Peipei, Wang, Ying, Yang, Dongjun, Li, Qixiang, Zeng, Xiangwei, Li, Xinyu, Hu, Ruifeng, Ge, Jingru, Yu, Zenong, Chen, Yugen, Chen, Bing, Ju, Junyi, Zhao, Quan
Format: Artigo
Idioma:Inglês
Publicat: Ivyspring International Publisher 2020
Matèries:
Research Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7150477/
https://ncbi.nlm.nih.gov/pubmed/32292506
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/thno.42047
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