The TMEM189 gene encodes plasmanylethanolamine desaturase which introduces the characteristic vinyl ether double bond into plasmalogens

A significant fraction of the glycerophospholipids in the human body is composed of plasmalogens, particularly in the brain, cardiac, and immune cell membranes. A decline in these lipids has been observed in such diseases as Alzheimer’s and chronic obstructive pulmonary disease. Plasmalogens contain...

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Publicat a:Proc Natl Acad Sci U S A
Autors principals: Werner, Ernst R., Keller, Markus A., Sailer, Sabrina, Lackner, Katharina, Koch, Jakob, Hermann, Martin, Coassin, Stefan, Golderer, Georg, Werner-Felmayer, Gabriele, Zoeller, Raphael A., Hulo, Nicolas, Berger, Johannes, Watschinger, Katrin
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2020
Matèries:
Biological Sciences
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7149458/
https://ncbi.nlm.nih.gov/pubmed/32209662
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1917461117
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