Abstinence-dependent dissociable central amygdala microcircuits control drug craving

We recently reported that social choice-induced voluntary abstinence prevents incubation of methamphetamine craving in rats. This inhibitory effect was associated with activation of protein kinase-Cδ (PKCδ)-expressing neurons in central amygdala lateral division (CeL). In contrast, incubation of cra...

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Udgivet i:Proc Natl Acad Sci U S A
Main Authors: Venniro, Marco, Russell, Trinity I., Ramsey, Leslie A., Richie, Christopher T., Lesscher, Heidi M. B., Giovanetti, Simone M., Messing, Robert O., Shaham, Yavin
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2020
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7148559/
https://ncbi.nlm.nih.gov/pubmed/32205443
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2001615117
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