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Long Term Pharmacological Perturbation of Autophagy in Mice: Are HCQ Injections a Relevant Choice?

Macroautophagy (hereafter referred to as autophagy) is an evolutionarily conserved catabolic process whose loss-of-function has been linked to a growing list of pathologies. Knockout mouse models of key autophagy genes have been instrumental in the demonstration of the critical functions of autophag...

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Detalhes bibliográficos
Publicado no:Biomedicines
Main Authors: Masson, Jean-Daniel, Blanchet, Benoit, Periou, Baptiste, Authier, François-Jérôme, Mograbi, Baharia, Gherardi, Romain K., Crépeaux, Guillemette
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7148514/
https://ncbi.nlm.nih.gov/pubmed/32121613
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biomedicines8030047
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