Population Pharmacokinetic Modeling and Pharmacodynamic Target Attainment Simulation of Piperacillin/Tazobactam for Dosing Optimization in Late Elderly Patients with Pneumonia

The aim of this study was to develop a population pharmacokinetic model for piperacillin (PIPC)/tazobactam (TAZ) in late elderly patients with pneumonia and to optimize the administration planning by applying pharmacokinetic/pharmacodynamic (PK/PD) criteria. PIPC/TAZ (total dose of 2.25 or 4.5 g) wa...

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Detalhes bibliográficos
Publicado no:Antibiotics (Basel)
Main Authors: Ishihara, Noriyuki, Nishimura, Nobuhiro, Ikawa, Kazuro, Karino, Fumi, Miura, Kiyotaka, Tamaki, Hiroki, Yano, Takahisa, Isobe, Takeshi, Morikawa, Norifumi, Naora, Kohji
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7148462/
https://ncbi.nlm.nih.gov/pubmed/32155905
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/antibiotics9030113
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