Successful High-Dosage Monotherapy of Tigecycline in a Multidrug-Resistant Klebsiella pneumoniae Pneumonia–Septicemia Model in Rats

Background: Recent scientific reports on the use of high dose tigecycline monotherapy as a “drug of last resort” warrant further research into the use of this regimen for the treatment of severe multidrug-resistant, Gram-negative bacterial infections. In the current study, the therapeutic efficacy o...

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Vydáno v:Antibiotics (Basel)
Hlavní autoři: Van der Weide, Hessel, Ten Kate, Marian T., Vermeulen-de Jongh, Denise M. C., Van der Meijden, Aart, Wijma, Rixt A., Boers, Stefan A., Van Westreenen, Mireille, Hays, John P., Goessens, Wil H. F., Bakker-Woudenberg, Irma A. J. M.
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2020
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7148456/
https://ncbi.nlm.nih.gov/pubmed/32138210
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/antibiotics9030109
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