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Comparison of commercially available whole-genome sequencing kits for variant detection in circulating cell-free DNA
Circulating cell-free DNA (ccfDNA) has great potential for non-invasive diagnosis, prognosis and monitoring treatment of disease. However, a sensitive and specific whole-genome sequencing (WGS) method is required to identify novel genetic variations (i.e., SNVs, CNVs and INDELS) on ccfDNA that can b...
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| Publié dans: | Sci Rep |
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| Auteurs principaux: | , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Nature Publishing Group UK
2020
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7148341/ https://ncbi.nlm.nih.gov/pubmed/32277101 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-63102-8 |
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