Pericentromeric heterochromatin is hierarchically organized and spatially contacts H3K9me2 islands in euchromatin

Membraneless pericentromeric heterochromatin (PCH) domains play vital roles in chromosome dynamics and genome stability. However, our current understanding of 3D genome organization does not include PCH domains because of technical challenges associated with repetitive sequences enriched in PCH geno...

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Publicado en:PLoS Genet
Autores principales: Lee, Yuh Chwen G., Ogiyama, Yuki, Martins, Nuno M. C., Beliveau, Brian J., Acevedo, David, Wu, C.-ting, Cavalli, Giacomo, Karpen, Gary H.
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2020
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7147806/
https://ncbi.nlm.nih.gov/pubmed/32203508
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1008673
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