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Biochemical characterization of the Nocardia lactamdurans ACV synthetase

The L-δ-(α-aminoadipoyl)-L-cysteinyl-D-valine synthetase (ACVS) is a nonribosomal peptide synthetase (NRPS) that fulfills a crucial role in the synthesis of β-lactams. Although some of the enzymological aspects of this enzyme have been elucidated, its large size, at over 400 kDa, has hampered hetero...

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發表在:PLoS One
Main Authors: Iacovelli, Riccardo, Zwahlen, Reto D., Bovenberg, Roel A. L., Driessen, Arnold J. M.
格式: Artigo
語言:Inglês
出版: Public Library of Science 2020
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC7147772/
https://ncbi.nlm.nih.gov/pubmed/32275728
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0231290
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