Investigating AKT activation and autophagy in immunoproteasome-deficient retinal cells

Two major proteolytic systems, the proteasome and the autophagy pathway, are key components of the proteostasis network. The immunoproteasome, a proteasome subtype, and autophagy are upregulated under stress conditions, forming a coordinated unit designed to minimize the effect of cell stress. We in...

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Gepubliceerd in:PLoS One
Hoofdauteurs: Karim, Md. Razaul, Fisher, Cody R., Kapphahn, Rebecca J., Polanco, Jorge R., Ferrington, Deborah A.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science 2020
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Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7147741/
https://ncbi.nlm.nih.gov/pubmed/32275682
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0231212
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