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Molecular and Cellular Alterations Induced by Sustained Expression of Ciliary Neurotrophic Factor in a Mouse Model of Retinitis Pigmentosa

PURPOSE. To characterize molecular and cellular changes induced by sustained expression of ciliary neurotrophic factor (CNTF) in the rds mutant mouse retina. METHODS. Recombinant adeno-associated virus (rAAV) expressing CNTF was injected subretinally, for transduction of peripherin/rds(+/−) transgen...

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Detalhes bibliográficos
Publicado no:Invest Ophthalmol Vis Sci
Main Authors: Rhee, Kun Do, Ruiz, Alberto, Duncan, Jacque L., Hauswirth, William W., LaVail, Matthew M., Bok, Dean, Yang, Xian-Jie
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7147570/
https://ncbi.nlm.nih.gov/pubmed/17325188
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.06-0677
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