A phase 2b, randomized, placebo-controlled, double-blind, dose-ranging study of the neurokinin 3 receptor antagonist fezolinetant for vasomotor symptoms associated with menopause

OBJECTIVE: Menopausal vasomotor symptoms (VMS) may result from altered thermoregulatory control in brain regions innervated by neurokinin 3 receptor-expressing neurons. This phase 2b study evaluated seven dosing regimens of fezolinetant, a selective neurokinin 3 receptor antagonist, as a nonhormone...

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Detalhes bibliográficos
Publicado no:Menopause
Main Authors: Fraser, Graeme L., Lederman, Samuel, Waldbaum, Arthur, Kroll, Robin, Santoro, Nanette, Lee, Misun, Skillern, Laurence, Ramael, Steven
Formato: Artigo
Idioma:Inglês
Publicado em: Lippincott-Raven Publishers 2020
Assuntos:
Original Studies
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7147405/
https://ncbi.nlm.nih.gov/pubmed/32102086
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/GME.0000000000001510
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