Neutrophil L-Plastin Controls Ocular Paucibacteriality and Susceptibility to Keratitis

Why ocular mucosa is paucibacterial is unknown. Many different mechanisms have been suggested but the comprehensive experimental studies are sparse. We found that a deficiency in L-plastin (LCP1), an actin bundling protein, resulted in an ocular commensal overgrowth, characterized with increased pre...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Lu, Xiaoxiao, Kugadas, Abirami, Smith-Page, Kirsten, Lamb, Jeffrey, Lin, Tiffany, Ru, Yusha, Morley, Sharon Celeste, Fichorova, Raina, Mittal, Sharad K., Chauhan, Sunil K., Littleton, Sejiro, Saban, Daniel, Gadjeva, Mihaela
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7147296/
https://ncbi.nlm.nih.gov/pubmed/32318063
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.00547
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