MiR-146a Ameliorates Hemoglobin-Induced Microglial Inflammatory Response via TLR4/IRAK1/TRAF6 Associated Pathways

Microglial activation and sustained inflammation in the brain can lead to neuronal damage. Hence, limiting microglial activation and brain inflammation is a good therapeutic strategy for inflammatory-associated central nervous disease. MiR-146a is a promising therapeutic microRNA, since it can negat...

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Enregistré dans:
Détails bibliographiques
Publié dans:Front Neurosci
Auteurs principaux: Liu, Guang-Jie, Zhang, Qing-Rong, Gao, Xuan, Wang, Han, Tao, Tao, Gao, Yong-Yue, Zhou, Yan, Chen, Xiang-Xin, Li, Wei, Hang, Chun-Hua
Format: Artigo
Langue:Inglês
Publié: Frontiers Media S.A. 2020
Sujets:
Neuroscience
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7147172/
https://ncbi.nlm.nih.gov/pubmed/32317924
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnins.2020.00311
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