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Fission and fusion machineries converge at ER contact sites to regulate mitochondrial morphology

The steady-state morphology of the mitochondrial network is maintained by a balance of constitutive fission and fusion reactions. Disruption of this steady-state morphology results in either a fragmented or elongated network, both of which are associated with altered metabolic states and disease. Ho...

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Pubblicato in:J Cell Biol
Autori principali: Abrisch, Robert G., Gumbin, Samantha C., Wisniewski, Brett Taylor, Lackner, Laura L., Voeltz, Gia K.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Rockefeller University Press 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7147108/
https://ncbi.nlm.nih.gov/pubmed/32328629
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201911122
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