Alternatively activated macrophages are associated with the α2AP production that occurs with the development of dermal fibrosis: The role of alternatively activated macrophages on the development of fibrosis

BACKGROUND: Fibrotic diseases are characterized by tissue overgrowth, hardening, and/or scarring because of the excessive production, deposition, and contraction of the extracellular matrix (ECM). However, the detailed mechanisms underlying these disorders remain unclear. It was recently reported th...

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Veröffentlicht in:Arthritis Res Ther
Hauptverfasser: Kanno, Yosuke, Shu, En, Niwa, Hirofumi, Kanoh, Hiroyuki, Seishima, Mariko
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2020
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7146905/
https://ncbi.nlm.nih.gov/pubmed/32272967
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13075-020-02159-2
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