Design of a Functionalized Metal–Organic Framework System for Enhanced Targeted Delivery to Mitochondria

[Image: see text] Mitochondria play a key role in oncogenesis and constitute one of the most important targets for cancer treatments. Although the most effective way to deliver drugs to mitochondria is by covalently linking them to a lipophilic cation, the in vivo delivery of free drugs still consti...

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Detalhes bibliográficos
Publicado no:J Am Chem Soc
Main Authors: Haddad, Salame, Abánades Lázaro, Isabel, Fantham, Marcus, Mishra, Ajay, Silvestre-Albero, Joaquin, Osterrieth, Johannes W. M., Kaminski Schierle, Gabriele S., Kaminski, Clemens F., Forgan, Ross S., Fairen-Jimenez, David
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2020
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7146860/
https://ncbi.nlm.nih.gov/pubmed/32182066
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.0c00188
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