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Differential effect of long-term systemic exposure of TNFα on health of the annulus fibrosus and nucleus pulposus of the intervertebral disc
The inflammatory cytokine tumor necrosis factor alpha (TNFα) is considered to play a key role in the pathogenesis of intervertebral disc disease. To evaluate the importance of this cytokine we examined the inflammatory environment and spinal phenotype of 9-month-old hTNFα overexpressing (hTNFα-TG) m...
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| Publicado no: | J Bone Miner Res |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7145745/ https://ncbi.nlm.nih.gov/pubmed/31800975 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jbmr.3931 |
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