Frequent template switching in postreplication gaps: suppression of deleterious consequences by the Escherichia coli Uup and RadD proteins

When replication forks encounter template DNA lesions, the lesion is simply skipped in some cases. The resulting lesion-containing gap must be converted to duplex DNA to permit repair. Some gap filling occurs via template switching, a process that generates recombination-like branched DNA intermedia...

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Udgivet i:Nucleic Acids Res
Main Authors: Romero, Zachary J, Armstrong, Thomas J, Henrikus, Sarah S, Chen, Stefanie H, Glass, David J, Ferrazzoli, Alexander E, Wood, Elizabeth A, Chitteni-Pattu, Sindhu, van Oijen, Antoine M, Lovett, Susan T, Robinson, Andrew, Cox, Michael M
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2020
Fag:
Genome Integrity, Repair and Replication
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7145654/
https://ncbi.nlm.nih.gov/pubmed/31665437
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkz960
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